Large Pore-Sized Hollow Mesoporous Organosilica for Redox-Responsive Gene Delivery and Synergistic Cancer Chemotherapy

CORC > 上海硅酸盐研究所 > 中国科学院上海硅酸盐研究所 > 高性能陶瓷和超微结构国家重点实验室 > 期刊论文

	Large Pore-Sized Hollow Mesoporous Organosilica for Redox-Responsive Gene Delivery and Synergistic Cancer Chemotherapy
	Wu, Meiying 1; Meng, Qingshuo 2; Chen, Yu 1; Zhang, Lingxia 1; Li, Mengli 1; Cai, Xiaojun 1; Li, Yaping 2; Yu, Pengcheng 2; Zhang, Linlin 1; Shi, Jianlin 1
刊名	ADVANCED MATERIALS
	2016-03-09
卷号	28 期号:10 页码:1963-+
英文摘要	A stability-difference-selective bond-breakage strategy for the fabrication of large-pore-sized hollow mesoporous organosilica nanoparticles (HMONs) is successfully developed. Moreover, surface-functionalized HMONs are successfully constructed to simultaneously deliver P-gp modulator siRNA and anticancer drug doxorubicin to reverse the multidrug resistance of cancer cells.
WOS标题词	Science & Technology ; Physical Sciences ; Technology
类目[WOS]	Chemistry, Multidisciplinary ; Chemistry, Physical ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary ; Physics, Applied ; Physics, Condensed Matter
研究领域[WOS]	Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics
关键词[WOS]	OVERCOMING MULTIDRUG-RESISTANCE ; SILICA NANOPARTICLES ; BIOMEDICAL APPLICATIONS ; ULTRALARGE PORES ; FACILE SYNTHESIS ; DRUG-DELIVERY ; BREAST-CANCER ; CO-DELIVERY ; RNA ; SPHERES
收录类别	SCI
语种	英语
WOS记录号	WOS:000372308700007
内容类型	期刊论文
源URL	[http://ir.sic.ac.cn/handle/331005/23166]
专题	上海硅酸盐研究所_高性能陶瓷和超微结构国家重点实验室_期刊论文
作者单位	1.Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, 1295 Ding Xi Rd, Shanghai 200050, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Mat Med, 501 Haike Rd, Shanghai 201203, Peoples R China
推荐引用方式 GB/T 7714	Wu, Meiying,Meng, Qingshuo,Chen, Yu,et al. Large Pore-Sized Hollow Mesoporous Organosilica for Redox-Responsive Gene Delivery and Synergistic Cancer Chemotherapy[J]. ADVANCED MATERIALS,2016,28(10):1963-+.
APA	Wu, Meiying.,Meng, Qingshuo.,Chen, Yu.,Zhang, Lingxia.,Li, Mengli.,...&Shi, Jianlin.(2016).Large Pore-Sized Hollow Mesoporous Organosilica for Redox-Responsive Gene Delivery and Synergistic Cancer Chemotherapy.ADVANCED MATERIALS,28(10),1963-+.
MLA	Wu, Meiying,et al."Large Pore-Sized Hollow Mesoporous Organosilica for Redox-Responsive Gene Delivery and Synergistic Cancer Chemotherapy".ADVANCED MATERIALS 28.10(2016):1963-+.