Brain-wide map of projections from mice ventral subiculum

CORC > 昆明植物研究所 > 中国科学院昆明植物研究所 > 植物化学与西部植物资源持续利用国家重点实验室

	Brain-wide map of projections from mice ventral subiculum
	Tang, He 1,2; Wu, Gui-Sheng1 ; Xie, Jing 1,2; He, Xiaobin 3; Deng, Ke 1; Wang, Huadong 3; Xu, Fuqiang 3,4; Luo, Huai-Rong1
刊名	NEUROSCIENCE LETTERS
	2016-08-26
卷号	629 页码:171-179
关键词	Hippocampal formation Ventral subiculum Herpes simplex virus Neural circuits Brain map
英文摘要	The hippocampal formation plays a critical role in episodic memory formation and spatial navigation. Within the hippocampus, the subiculum is considered to be a hub connecting the hippocampal formation to the remainder of the brain. There are functional differences between the dorsal and ventral part of subiculum, while the ventral subiculum (vSub) plays a role in anxiety, stress and emotion. In the present study, we examined the projection of the ventral subiculum to the whole brain in mice by using a modified herpes simplex virus 1 strain H129 with an inserted fluorescent protein gene. In our experiments, the modified H129 transits the primary-order, second-order, and third-order neuronal projections at 36-44, 52-60 and 68-76 h after inoculation in mice, respectively. Our data revealed that vSub directly projects to the medial entorhinal cortex, amygdalohippocampal area, anterodorsal thalamic nucleus, medial hypothalamus, supramammillary nucleus, medial septal nucleus and adjacent diagonal band, the connections between median raphe nucleus and interpeduncular nucleus in brain stem, while ventral prefrontal cortex, laterodorsal tegmental nucleus and locus coeruleus receives second-order projections from vSub. Our data would help further understanding the functional connections of vSub with other brain regions. (C) 2016 Elsevier Ireland Ltd. All rights reserved.
类目[WOS]	Neurosciences
研究领域[WOS]	Neurosciences & Neurology
关键词[WOS]	PHASEOLUS-VULGARIS-LEUKOAGGLUTININ ; TOPOGRAPHICAL ORGANIZATION ; ENTORHINAL CORTEX ; HIPPOCAMPAL CA1 ; RAT ; CONNECTIONS ; NEURONS ; PATTERNS ; HYPOTHALAMUS ; MORPHOLOGY
收录类别	SCI
语种	英语
WOS记录号	WOS:000382409000031
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn/handle/151853/33603]
专题	昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, 134 Lanhei Rd, Kunming 650201, Yunnan, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100039, Peoples R China 3.Chinese Acad Sci, Wuhan Inst Phys & Math, State Key Lab Magnet Resonance & Atom & Mol Phys, Wuhan 430071, Peoples R China 4.Wuhan Natl Lab Optoelect, Wuhan 430074, Peoples R China
推荐引用方式 GB/T 7714	Tang, He,Wu, Gui-Sheng,Xie, Jing,et al. Brain-wide map of projections from mice ventral subiculum[J]. NEUROSCIENCE LETTERS,2016,629:171-179.
APA	Tang, He.,Wu, Gui-Sheng.,Xie, Jing.,He, Xiaobin.,Deng, Ke.,...&Luo, Huai-Rong.(2016).Brain-wide map of projections from mice ventral subiculum.NEUROSCIENCE LETTERS,629,171-179.
MLA	Tang, He,et al."Brain-wide map of projections from mice ventral subiculum".NEUROSCIENCE LETTERS 629(2016):171-179.