Near-Infrared (NIR)-Absorbing Conjugated Polymer Dots as Highly Effective Photothermal Materials for In Vivo Cancer Therapy

	Near-Infrared (NIR)-Absorbing Conjugated Polymer Dots as Highly Effective Photothermal Materials for In Vivo Cancer Therapy
	Li, Shengliang 1; Wang, Xiaoyu 1; Hu, Rong 1; Chen, Hui 1; Li, Meng 1; Wang, Jianwu 1; Wang, Yunxia 1; Liu, Libing 1; Lv, Fengting 1; Liang, Xing-Jie 2
刊名	CHEMISTRY OF MATERIALS
	2016-12-13
卷号	28 期号:23 页码:8669-8675
英文摘要	Photothermal therapy (PTT) holds great promise for noninvasive cancer treatment. To fulfill this goal, highly effective and low-risk photothermal agents have been intensively explored. Here, we present a new PTT material based on conjugated polymer dots (Pdots) that exhibit strong near-infrared (NIR) absorption and high photostability. The Pdots result in a thermal response upon illumination with a NIR laser, leading to a high photothermal conversion efficiency of 65%. Thus, the photothermal ablation of cancer cells using the Pdots both in vitro and in vivo can be achieved, highlighting the potential of Pdots as a nanoplatform for clinical therapy. They also open up a new avenue to develop new photothermal therapeutic materials.
收录类别	SCI
语种	英语
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/36517]
专题	化学研究所_有机固体实验室
作者单位	1.Chinese Acad Sci, Inst Chem, Key Lab Organ Solids, Beijing Natl Lab Mol Sci, Beijing 100190, Peoples R China 2.Chinese Acad Sci, Natl Ctr Nanosci & Technol, CAS Key Lab Biol Effects Nanomat & Nanosafety, Ctr Excellence Nanosci, Beijing 100190, Peoples R China
推荐引用方式 GB/T 7714	Li, Shengliang,Wang, Xiaoyu,Hu, Rong,et al. Near-Infrared (NIR)-Absorbing Conjugated Polymer Dots as Highly Effective Photothermal Materials for In Vivo Cancer Therapy[J]. CHEMISTRY OF MATERIALS,2016,28(23):8669-8675.
APA	Li, Shengliang.,Wang, Xiaoyu.,Hu, Rong.,Chen, Hui.,Li, Meng.,...&Wang, Shu.(2016).Near-Infrared (NIR)-Absorbing Conjugated Polymer Dots as Highly Effective Photothermal Materials for In Vivo Cancer Therapy.CHEMISTRY OF MATERIALS,28(23),8669-8675.
MLA	Li, Shengliang,et al."Near-Infrared (NIR)-Absorbing Conjugated Polymer Dots as Highly Effective Photothermal Materials for In Vivo Cancer Therapy".CHEMISTRY OF MATERIALS 28.23(2016):8669-8675.