Enabling Prussian Blue with Tunable Localized Surface Plasmon Resonances: Simultaneously Enhanced Dual-Mode Imaging and Tumor Photothermal Therapy | |
Cai, Xiaojun1,2; Gao, Wei3; Zhang, Linlin1,2; Ma, Ming1; Liu, Tianzhi1,2; Du, Wenxian1,2; Zheng, Yuanyi3; Chen, Hangrong1; Shi, Jianlin1 | |
刊名 | ACS NANO |
2016-12-01 | |
卷号 | 10期号:12页码:11115-11126 |
关键词 | Prussian blue tunable localized surface plasmon resonances magnetic resonance imaging photoacoustic imaging photothermal therapy reactive oxygen species scavenger |
英文摘要 | Prussian blue (PB) has been used as a photothermal conversion agent to generate heat to induce localized damage "to tumor. However, its therapeutic efficiency is far from satisfactory. One of the major obstacles is that the maximum NIR absorption peak of PB within 690-720 nm cannot be optimized near the wavelength of the laser to enhance its therapeutic efficiency. Herein, we report that the integration of Gd3+ into PB nanocrystals (GPB NCs) enables PB with tunable localized surface plasmon resonances (LSPRs) from 710 to 910 nm, achieving the maximum NIR peak near the wavelength of the laser. Concurrently, the efficiency of dual-mode imaging including photo acoustic imaging and magnetic resonance imaging has been greatly improved. These enhancements in dual-mode imaging and photo thermal therapy enable PB with low nanomaterial dose and laser flux. Additionally, it is found that GPB NCs show the capability of not only acting as a chemical probe with tunable sensitivity but also scavenging reactive functional ions into a photothermal conversion agent is an efficient strategy to enchanting tumor theranostic efficiency. oxygen species. The integration of improve the synergy of nanoagent, |
WOS标题词 | Science & Technology ; Physical Sciences ; Technology |
类目[WOS] | Chemistry, Multidisciplinary ; Chemistry, Physical ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary |
研究领域[WOS] | Chemistry ; Science & Technology - Other Topics ; Materials Science |
关键词[WOS] | COATED GOLD NANOPARTICLES ; LONG-TERM STABILITY ; SENSING APPLICATIONS ; OXIDE NANOCRYSTALS ; QUALITY ASSESSMENT ; THERANOSTIC AGENT ; THALLIUM BINDING ; WATER-CONTENT ; CANCER ; METAL |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000391079700055 |
内容类型 | 期刊论文 |
源URL | [http://ir.sic.ac.cn/handle/331005/21892] |
专题 | 上海硅酸盐研究所_高性能陶瓷和超微结构国家重点实验室_期刊论文 |
作者单位 | 1.Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, Shanghai 200050, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Shanghai Jiao Tong Univ, Sch Med, Shanghai Peoples Hosp 6, Shanghai 200233, Peoples R China |
推荐引用方式 GB/T 7714 | Cai, Xiaojun,Gao, Wei,Zhang, Linlin,et al. Enabling Prussian Blue with Tunable Localized Surface Plasmon Resonances: Simultaneously Enhanced Dual-Mode Imaging and Tumor Photothermal Therapy[J]. ACS NANO,2016,10(12):11115-11126. |
APA | Cai, Xiaojun.,Gao, Wei.,Zhang, Linlin.,Ma, Ming.,Liu, Tianzhi.,...&Shi, Jianlin.(2016).Enabling Prussian Blue with Tunable Localized Surface Plasmon Resonances: Simultaneously Enhanced Dual-Mode Imaging and Tumor Photothermal Therapy.ACS NANO,10(12),11115-11126. |
MLA | Cai, Xiaojun,et al."Enabling Prussian Blue with Tunable Localized Surface Plasmon Resonances: Simultaneously Enhanced Dual-Mode Imaging and Tumor Photothermal Therapy".ACS NANO 10.12(2016):11115-11126. |
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