Abnormal regional homogeneity of drug-naive obsessive-compulsive patients

CORC > 昆明动物研究所 > 昆明动物研究所 > 动物模型与人类重大疾病机理重点实验室 > 学习记忆的分子神经机制

	Abnormal regional homogeneity of drug-naive obsessive-compulsive patients
	Yang T 1; Cheng YQ 1,2,4; Li HJ 3; Jiang HY 1; Luo CR 3; Shan BC 5; Xu L 2,4; Xu XF[*]1
刊名	NEUROREPORT
	2010
卷号	21 期号:11 页码:786-790
关键词	functional magnetic resonance imaging obsessive-compulsive disorder regional homogeneity resting-state
ISSN号	0959-4965
通讯作者	xfxu2004@sina.com
合作状况	其它
英文摘要	To explore the possible abnormal resting-state activity in patients with obsessive-compulsive disorder (OCD), the regional homogeneity (ReHo) of 22 pairs of patients and well-matched healthy controls was calculated. Compared with controls, the patients showed higher ReHo in the left anterior cingulate cortex, but lower ReHo in the left inferior temporal gyrus. These findings supported the abnormal resting-state brain activity in drug-naive OCD patients. No significant correlations between ReHo value and four clinical characteristics were found, suggesting that abnormal ReHo might be trait-related in OCD.
学科主题	Neurosciences
收录类别	SCI
资助信息	This work was supported by United Funding of Yunnan Provincial Science and Technology Department and Kunming Medical College (2008C005R) and the Funding of Yunnan Provincial Health Science and Technology Plan (2009 NS096,2009NS092).
语种	英语
公开日期	2010-08-24
内容类型	期刊论文
源URL	[http://159.226.149.42:8088/handle/152453/5937]
专题	昆明动物研究所_学习记忆的分子神经机制昆明动物研究所_动物模型与人类重大疾病机理重点实验室
作者单位	1.Department of Psychiatry, The First Affiliated Hospital of Kunming Medical College 2.Key Laboratory of Animal Models and Human Disease Mechanisms, Chinese Academy of Sciences, Kunming Institute of Zoology 3.Magnetic Resonance Imaging Center,The First Hospital of Kunming City, Kunming,Yunnan 4.Graduate School of Chinese Academy of Sciences 5.Institute of High Energy Physics, Chinese Academy of Sciences, Beijing, China
推荐引用方式 GB/T 7714	Yang T,Cheng YQ,Li HJ,et al. Abnormal regional homogeneity of drug-naive obsessive-compulsive patients[J]. NEUROREPORT,2010,21(11):786-790.
APA	Yang T.,Cheng YQ.,Li HJ.,Jiang HY.,Luo CR.,...&Xu XF[*].(2010).Abnormal regional homogeneity of drug-naive obsessive-compulsive patients.NEUROREPORT,21(11),786-790.
MLA	Yang T,et al."Abnormal regional homogeneity of drug-naive obsessive-compulsive patients".NEUROREPORT 21.11(2010):786-790.