Changes of urinary steroid conjugates and gonadotropin excretion in the menstrual cycle and pregnancy in the Yunnan snub-nosed monkey (Rhinopithecus bieti)

	Changes of urinary steroid conjugates and gonadotropin excretion in the menstrual cycle and pregnancy in the Yunnan snub-nosed monkey (Rhinopithecus bieti)
	He YM; Pei YJ; Zou RJ; Ji WZ[*]
刊名	AMERICAN JOURNAL OF PRIMATOLOGY
	2001
卷号	55 期号:4 页码:223-232
关键词	Rhinopithecus bieti menstrual cycle estrone conjugates (E1C) pregnanediol-3-glucuronide (PdG) LH FSH
ISSN号	0275-2565
通讯作者	wji@mail.kiz.ac.cn
合作状况	其它
英文摘要	The Yunnan snub-nosed monkey (Rhinopithecus bieti) is one of the most endangered species in the world, and it is endemic to China. According to our knowledge, there was no information on reproduction for this species. The present study was designed to understand the characteristics of reproductive hormone secretion during the menstrual cycle and pregnancy of this species by monitoring urinary estrone conjugate (E1C), pregnanediol-3-glucuronide (PdG), bioactive follicle-stimulating hormone (FSH), and luteinizing hormone (LH). The urine samples were collected each day from four adult females for eight menstrual cycles, and once in 3 days during pregnancy (three full-term pregnancies, one mid-term abortion). The steroid conjugate was tested by radioimmunoassays (RIAs), and bioactive FSH and LH levels were measured in vitro by the sensitive bioassays granulosa cell aromatize bioassay (GAB) and rat interstitial cell testosterone (RICT), respectively. The results showed that: 1) E1C presented a preovulatory peak (183.9 +/- 8.6 ng/mgCr) followed by a definite elevation of PdG; 2) PdG in the luteal phase (754.4 +/- 30.6 ng/mgCr) was three- to fivefold higher than during the corresponding follicular phase (198.3 +/- 11.4 ng/mgCr); 3) the peaks of bio-LH and bio-FSH were on the same day, while the E1C peak was 1 or 2 days before the peaks for these two hormones; 4) bio-FSH levels were higher in the follicular phase than in the luteal phase, and bio-LH levels elevated slightly in the luteal phase; 5) the mean cycle length was 23.6 +/- 3.5 days (n = 3) based upon successive urinary LH peaks; 6) based on the interval from the day of E1C peak to the day of parturition, the gestation was 203.7 +/- 2.5 days (n = 3); and 7) both E1C and PdG increased and remained high after pregnancy, with a sharp decrease in basal levels following parturition or mid-term abortion. The results suggested that the pattern of reproductive hormones for R. bieti is similar to that of other Old World monkeys, but the concentration of the hormones is different from that of other species. This species has a longer progestation period, which may be related to its classification status.
收录类别	SCI
资助信息	State Research Development Program; Contract grant number: G20000168108. Chinese Academy of Sciences; Contract grant number: KXCX1-05-02.
原文出处	200155223.pdf
语种	英语
公开日期	2010-08-24
内容类型	期刊论文
源URL	[http://159.226.149.42:8088/handle/152453/5547]
专题	昆明动物研究所_生殖与发育生物学
作者单位	Kunming Institute of Zoology, Chinese Academy of Sciences, Yunnan, China
推荐引用方式 GB/T 7714	He YM,Pei YJ,Zou RJ,et al. Changes of urinary steroid conjugates and gonadotropin excretion in the menstrual cycle and pregnancy in the Yunnan snub-nosed monkey (Rhinopithecus bieti)[J]. AMERICAN JOURNAL OF PRIMATOLOGY,2001,55(4):223-232.
APA	He YM,Pei YJ,Zou RJ,&Ji WZ[*].(2001).Changes of urinary steroid conjugates and gonadotropin excretion in the menstrual cycle and pregnancy in the Yunnan snub-nosed monkey (Rhinopithecus bieti).AMERICAN JOURNAL OF PRIMATOLOGY,55(4),223-232.
MLA	He YM,et al."Changes of urinary steroid conjugates and gonadotropin excretion in the menstrual cycle and pregnancy in the Yunnan snub-nosed monkey (Rhinopithecus bieti)".AMERICAN JOURNAL OF PRIMATOLOGY 55.4(2001):223-232.