Lancifodilactone G: A unique nortriterpenoid isolated from Schisandra lancifolia and its anti-HIV activity

CORC > 昆明动物研究所 > 昆明动物研究所 > 动物模型与人类重大疾病机理重点实验室 > 分子免疫药理学

	Lancifodilactone G: A unique nortriterpenoid isolated from Schisandra lancifolia and its anti-HIV activity
	Xiao WL 1,2; Zhu HJ 1; Shen YH 1,2; Li RT[]1; Li SH 1; Sun HD[]1; Zheng YT 3; Wang RR 3; Lu Y 4; Wang C 4
刊名	ORGANIC LETTERS
	2005
卷号	7 期号:11 页码:2145-2148
ISSN号	1523-7060
通讯作者	hdsun@mail.kib.ac.cn
合作状况	其它
英文摘要	Lancifodilactone G (1), a novel, highly oxygenated nortriterpenoid featuring a partial enol structure and a spirocyclic moiety, was isolated from the medicinal plant Schisandra lancifolia. Its structure and stereochemistry were determined from extensive one- and two-dimensional NMR and mass spectral data, coupled with single-crystal X-ray analysis. Compound 1 exerted minimal cytotoxicity against C8166 cells (CC50 > 200 mu g/mL) and showed anti-HIV activity with EC50 = 95.47 +/- 14.19 mu g/mL and a selectivity index in the range of 1.82-2.46.
收录类别	SCI
资助信息	This project was supported by grants from the National Natural Science Foundation of China (No. 20402016, awarded to R. T. Li), Key Scientific and Tech- nological Projects of China (2004BA719A14) and Yunnan Province (2004NG12) to Y. T. Zheng, and “Hundreds Talents Program” from the Chinese Academy of Sciences to H. J. Zhu.
原文出处	200572145.pdf
语种	英语
公开日期	2010-08-24
内容类型	期刊论文
源URL	[http://159.226.149.42:8088/handle/152453/4543]
专题	昆明动物研究所_分子免疫药理学
作者单位	1.Kunming Institute of Botany 2.Graduate School of the Chinese Academy of Sciences 3.Kunming Institute of Zoology 4.Institute of Materia Medica
推荐引用方式 GB/T 7714	Xiao WL,Zhu HJ,Shen YH,et al. Lancifodilactone G: A unique nortriterpenoid isolated from Schisandra lancifolia and its anti-HIV activity[J]. ORGANIC LETTERS,2005,7(11):2145-2148.
APA	Xiao WL.,Zhu HJ.,Shen YH.,Li RT[*].,Li SH.,...&Zheng QT.(2005).Lancifodilactone G: A unique nortriterpenoid isolated from Schisandra lancifolia and its anti-HIV activity.ORGANIC LETTERS,7(11),2145-2148.
MLA	Xiao WL,et al."Lancifodilactone G: A unique nortriterpenoid isolated from Schisandra lancifolia and its anti-HIV activity".ORGANIC LETTERS 7.11(2005):2145-2148.