Enantioselective Construction of Spiroindolines with Three Contiguous Stereogenic Centers and Chiral Tryptamine Derivatives via Reactive Spiroindolenine Intermediates

CORC > 上海有机化学研究所 > 中国科学院上海有机化学研究所 > 金属有机化学国家重点实验室

	Enantioselective Construction of Spiroindolines with Three Contiguous Stereogenic Centers and Chiral Tryptamine Derivatives via Reactive Spiroindolenine Intermediates
	Zhuo CX(卓春祥)1; Zhou Y(周勇)1; Cheng Q(程强)1; Huang L(黄林)1; You SL(游书力)1
刊名	Angew. Chem.-Int. Edit.
	2015
卷号	54 期号:47 页码:14146-14149
其他题名	含有三个连续手性中心的螺吲哚啉以及通过活性螺吲哚啉中间体对于色胺衍生物的不对称构建
通讯作者	游书力
英文摘要	The highly efficient synthesis of the enantioenriched spiroindolines by iridium-catalyzed asymmetric allylic dearomatization and reduction is presented. Spiroindolines containing three contiguous stereogenic centers were obtained with excellent diastereo- and enantioselectivity. In addition, a chiral tryptamine derivative could be easily accessed in good yield with excellent ee value through an unprecedented dearomatization/retro-Mannich/hydrolysis cascade reaction of an indole derivative.
学科主题	金属有机化学
收录类别	SCI
原文出处	http://dx.doi.org/10.1002/anie.201507193
语种	英语
WOS记录号	WOS:000367722500057
内容类型	期刊论文
源URL	[http://ir.sioc.ac.cn/handle/331003/39684]
专题	上海有机化学研究所_金属有机化学国家重点实验室
作者单位	1.中科院上海有机化学研究所, 金属有机化学国家重点实验室 2.天津化学化工协同创新中心
推荐引用方式 GB/T 7714	Zhuo CX,Zhou Y,Cheng Q,et al. Enantioselective Construction of Spiroindolines with Three Contiguous Stereogenic Centers and Chiral Tryptamine Derivatives via Reactive Spiroindolenine Intermediates[J]. Angew. Chem.-Int. Edit.,2015,54(47):14146-14149.
APA	卓春祥,周勇,程强,黄林,&游书力.(2015).Enantioselective Construction of Spiroindolines with Three Contiguous Stereogenic Centers and Chiral Tryptamine Derivatives via Reactive Spiroindolenine Intermediates.Angew. Chem.-Int. Edit.,54(47),14146-14149.
MLA	卓春祥,et al."Enantioselective Construction of Spiroindolines with Three Contiguous Stereogenic Centers and Chiral Tryptamine Derivatives via Reactive Spiroindolenine Intermediates".Angew. Chem.-Int. Edit. 54.47(2015):14146-14149.