Antioxidative extracts and phenols isolated from Qinghai-Tibet Plateau medicinal plant Saxifraga tangutica Engl.

	Antioxidative extracts and phenols isolated from Qinghai-Tibet Plateau medicinal plant Saxifraga tangutica Engl.
	Dang, Jun; Tao, Yanduo; Shao, Yun; Mei, Lijuan; Zhang, Li; Wang, Qilan
刊名	industrial crops and products
	2015-12-30
卷号	78 页码:13-18
关键词	Saxifraga tangutica Engl. Antioxidative activity Phenols Qinghai-Tibet Plateau Liquid chromatography
英文摘要	saxifraga tangutica engl., is a medicinal herb that grows on the qinghai-tibet plateau. extracts and phenols fromthe qinghai population have been subjected to antioxidative assays against dpph radical-scavenging and reducing power (frap). the 50% ethanol extract showed strong antioxidative activity against dpph and frap, with ic50 +/- sem [mu g/ml] values of 9.38 +/- 0.46 and 15.46 +/- 0.52, respectively. the antioxidative activity-guided fractionations were performed according to the dpph and frap screening results. fourteen fractions from the 50% ethanol extract showed dissimilar antioxidative activity against dpph and frap of 8.16 +/- 0.76 similar to 38.42 +/- 0.58 mu g/ml and 13.22 +/- 0.68 similar to 61.47 +/- 0.49 mu g/ml. the chemical assayguided separation of the active fractions (fractions 3, 6, 7 and 8) led to eight phenols: protocatechuic aldehyde (1), ethyl gallate (2), rhododendrin (3), p-hydroxyacetophenone (4), rhododendrol (5), protocatechuic acid ethyl ester (6), frambinone (7) and ethylparaben (8). all phenols are reported here for the first time from s. tangutica engl. protocatechuic aldehyde (1), ethyl gallate (2), rhododendrin (3) and protocatechuic acid ethyl ester (6) showed strong antioxidative activities (ic50 +/- sem [mm] between 8.79 +/- 0.15 and 4.25 +/- 0.47 and between 6.15 +/- 0.48 and 2.83 +/- 0.49) against dpph and frap. (c) 2015 elsevier b.v. all rights reserved.
WOS标题词	science & technology ; life sciences & biomedicine
类目[WOS]	agricultural engineering ; agronomy
研究领域[WOS]	agriculture
关键词[WOS]	oxidase inhibitory-activity ; chemical-constituents ; in-vitro ; stolonifera ; l. ; rhododendrin ; alpha ; china
收录类别	SCI
语种	英语
WOS记录号	WOS:000366780100003
内容类型	期刊论文
源URL	[http://ir.nwipb.ac.cn/handle/363003/6512]
专题	西北高原生物研究所_中国科学院西北高原生物研究所
作者单位	Chinese Acad Sci, Northwest Inst Plateau Biol, Key Lab Tibetan Med Res, Xining, Peoples R China
推荐引用方式 GB/T 7714	Dang, Jun,Tao, Yanduo,Shao, Yun,et al. Antioxidative extracts and phenols isolated from Qinghai-Tibet Plateau medicinal plant Saxifraga tangutica Engl.[J]. industrial crops and products,2015,78:13-18.
APA	Dang, Jun,Tao, Yanduo,Shao, Yun,Mei, Lijuan,Zhang, Li,&Wang, Qilan.(2015).Antioxidative extracts and phenols isolated from Qinghai-Tibet Plateau medicinal plant Saxifraga tangutica Engl..industrial crops and products,78,13-18.
MLA	Dang, Jun,et al."Antioxidative extracts and phenols isolated from Qinghai-Tibet Plateau medicinal plant Saxifraga tangutica Engl.".industrial crops and products 78(2015):13-18.