Fluorescence turn-on strategy based on silver nanoclusters-Cu2+ system for trace detection of quinolones

	Fluorescence turn-on strategy based on silver nanoclusters-Cu2+ system for trace detection of quinolones
	Mao, Beibei 1,2; Qu, Fei 1,2; Zhu, Shuyun 1,2,3; You, Jinmao 1,2,3
刊名	sensors and actuators b-chemical
	2016-10-29
卷号	234 页码:338-344
关键词	Ag nanoclusters Polyethyleneimine Quinolones Trace detecion
英文摘要	herein, utilizing fluorescent ag nanoclusters (ag ncs) capped by polyethyleneimine (pei) with different molecular weights, we constructed a novel ag ncs-cu2+ sensing system based on fluorescence turn-on strategy for trace detection of quinolones, including nalidixic acid, cinoxacin, ciprofloxacin/ofloxacin, and moxifloxacin; these were the representatives of four generations of quinolone antibacterial drugs. the fluorescence of ag ncs could be efficiently quenched by cu2+, while with the addition of quinolones, the fluorescence of this system recovered rapidly. this protocol exhibited excellent sensitivities to these five quinolones. for instance, the linear ranges were from 1 to 100 nm for nalidixic acid with limit of detection (lod) 0.47 nm, from 1 to 80 nm for cinoxacin with lod 0.43 nm, from 0.1 to 120 nm for ciprofloxacin with lod 38 pm, from 0.1 to 80 nm for ofloxacin with lod 49 pm, and from 0.1 to 120 nm for moxifloxacin with lod 48 pm, respectively, revealing that this approach showed low detection limits and wide linear ranges. benefiting from the high sensitivity, the satisfactory recoveries were obtained for trace detection of quinolones in real samples, such as tablets, human urine and serum. (c) 2016 elsevier b.v. all rights reserved.
WOS标题词	science & technology ; physical sciences ; technology
类目[WOS]	chemistry, analytical ; electrochemistry ; instruments & instrumentation
研究领域[WOS]	chemistry ; electrochemistry ; instruments & instrumentation
关键词[WOS]	performance liquid-chromatography ; tandem mass-spectrometry ; capillary-zone-electrophoresis ; ultraviolet detection ; fluoroquinolones ; samples ; ciprofloxacin ; antibiotics ; moxifloxacin ; extraction
收录类别	SCI
语种	英语
WOS记录号	WOS:000378538700042
内容类型	期刊论文
源URL	[http://ir.nwipb.ac.cn/handle/363003/6479]
专题	西北高原生物研究所_中国科学院西北高原生物研究所
作者单位	1.Qufu Normal Univ, Key Lab Life Organ Anal, Qufu 273165, Shandong, Peoples R China 2.Qufu Normal Univ, Key Lab Pharmaceut Intermediates & Anal Nat Med, Qufu 273165, Shandong, Peoples R China 3.Chinese Acad Sci, Northwest Inst Plateau Biol, Xining 810001, Peoples R China
推荐引用方式 GB/T 7714	Mao, Beibei,Qu, Fei,Zhu, Shuyun,et al. Fluorescence turn-on strategy based on silver nanoclusters-Cu2+ system for trace detection of quinolones[J]. sensors and actuators b-chemical,2016,234:338-344.
APA	Mao, Beibei,Qu, Fei,Zhu, Shuyun,&You, Jinmao.(2016).Fluorescence turn-on strategy based on silver nanoclusters-Cu2+ system for trace detection of quinolones.sensors and actuators b-chemical,234,338-344.
MLA	Mao, Beibei,et al."Fluorescence turn-on strategy based on silver nanoclusters-Cu2+ system for trace detection of quinolones".sensors and actuators b-chemical 234(2016):338-344.