Isolation, Stereochemical Study, and Antioxidant Activity of Benzofuranone Derivatives from a Mangrove-derived Fungus Eurotium rubrum MA-150

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	Isolation, Stereochemical Study, and Antioxidant Activity of Benzofuranone Derivatives from a Mangrove-derived Fungus Eurotium rubrum MA-150
	Meng, Ling-Hong1,2 ; Mandi, Attila 3; Li, Xiao-Ming 1; Liu, Yang 1,2; Kurtan, Tibor 3; Wang, Bin-Gui1
刊名	CHIRALITY
	2016-08-01
卷号	28 期号:8 页码:581-584
关键词	marine-derived fungus benzofuran-1(3H)-one HPLC-ECD TDDFT calculations DPPH radical scavenging activity
英文摘要	Enantiomers of a 2-benzofuran-1(3H)-one derivative [(-)-1 and (+)-1] and four known analogs (2, 3, 4, 5) were isolated and identified from the culture extract of Eurotium rubrum MA-150, a fungus obtained from the mangrove-derived rizospheric soil. Their structures were established by detailed interpretation of nuclear magnetic resonance (NMR) data and the structure of (+/-)-1 was confirmed by single-crystal X-ray diffraction analysis. The absolute configuration of the enantiomers (-)-1 and (+)-1 was determined by means of online high-performance liquid chromatography - electronic circular dichroism (HPLC-ECD) measurements and time-dependent Density Functional Theory - electronic circular dichroism (TDDFT-ECD) calculations. Compounds (+/-)-1 as well as 2 and 3 exhibited potent DPPH radical scavenging activities with IC50 values of 1.23, 2.26, and 3.99 g/mL, respectively. Chirality 28:581-584, 2016. (c) 2016 Wiley Periodicals, Inc.
收录类别	SCI
语种	英语
WOS记录号	WOS:000380950600001
内容类型	期刊论文
版本	出版稿
源URL	[http://ir.qdio.ac.cn/handle/337002/135860]
专题	海洋研究所_实验海洋生物学重点实验室
作者单位	1.Chinese Acad Sci, Key Lab Expt Marine Biol, Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol,Inst Oceanol, Naihai Rd 7, Qingdao 266071, Peoples R China 2.Univ Chinese Acad Sci, Beijing, Peoples R China 3.Univ Debrecen, Dept Organ Chem, POB 400, H-4002 Debrecen, Hungary
推荐引用方式 GB/T 7714	Meng, Ling-Hong,Mandi, Attila,Li, Xiao-Ming,et al. Isolation, Stereochemical Study, and Antioxidant Activity of Benzofuranone Derivatives from a Mangrove-derived Fungus Eurotium rubrum MA-150[J]. CHIRALITY,2016,28(8):581-584.
APA	Meng, Ling-Hong,Mandi, Attila,Li, Xiao-Ming,Liu, Yang,Kurtan, Tibor,&Wang, Bin-Gui.(2016).Isolation, Stereochemical Study, and Antioxidant Activity of Benzofuranone Derivatives from a Mangrove-derived Fungus Eurotium rubrum MA-150.CHIRALITY,28(8),581-584.
MLA	Meng, Ling-Hong,et al."Isolation, Stereochemical Study, and Antioxidant Activity of Benzofuranone Derivatives from a Mangrove-derived Fungus Eurotium rubrum MA-150".CHIRALITY 28.8(2016):581-584.