Mesoporous silica nanoparticles with organo-bridged silsesquioxane framework as innovative platforms for bioimaging and therapeutic agent delivery

CORC > 过程工程研究所 > 中国科学院过程工程研究所 > 湿法冶金清洁生产技术国家工程实验室

	Mesoporous silica nanoparticles with organo-bridged silsesquioxane framework as innovative platforms for bioimaging and therapeutic agent delivery
	Du, Xin 1,5; Li, Xiaoyu 2; Xiong, Lin 5; Zhang, Xueji 1; Kleitz, Freddy 3,4; Qiao, Shi Zhang 5
刊名	BIOMATERIALS
	2016-06-01
卷号	91 期号:JUNE 页码:90-127
关键词	PMOs Mesoporous nanoparticles Biocompatible properties Advanced nanocarriers Bioimaging Therapeutic agent delivery
ISSN号	0142-9612
英文摘要	Mesoporous silica material with organo-bridged silsesquioxane frameworks is a kind of synergistic combination of inorganic silica, mesopores and organics, resulting in some novel or enhanced physicochemical and biocompatible properties compared with conventional mesoporous silica materials with pure Si-O composition. With the rapid development of nanotechnology, monodispersed nanoscale periodic mesoporous organosilica nanoparticles (PMO NPs) and organo-bridged mesoporous silica nano particles (MSNs) with various organic groups and structures have recently been synthesized from 100%, or less, bridged organosilica precursors, respectively. Since then, these materials have been employed as carrier platforms to construct bioimaging and/or therapeutic agent delivery nanosystems for nano biomedical application, and they demonstrate some unique and/or enhanced properties and performances. This review article provides a comprehensive overview of the controlled synthesis of PMO NPs and organ-bridged MSNs, physicochemical and biocompatible properties, and their nano-biomedical application as bioimaging agent and/or therapeutic agent delivery system. (c) 2016 Elsevier Ltd. All rights reserved.
WOS标题词	Science & Technology ; Technology
类目[WOS]	Engineering, Biomedical ; Materials Science, Biomaterials
研究领域[WOS]	Engineering ; Materials Science
关键词[WOS]	INORGANIC HYBRID MATERIALS ; DRUG-DELIVERY ; GENE DELIVERY ; HOLLOW SPHERES ; CANCER-CELLS ; BIOMEDICAL APPLICATIONS ; FLUORESCENT HYBRID ; PORE WALLS ; TOPOLOGICAL TRANSFORMATION ; SURFACE FUNCTIONALIZATION
收录类别	SCI
语种	英语
WOS记录号	WOS:000374611900008
内容类型	期刊论文
源URL	[http://ir.ipe.ac.cn/handle/122111/21015]
专题	过程工程研究所_湿法冶金清洁生产技术国家工程实验室
作者单位	1.Univ Sci & Technol Beijing, Res Ctr Bioengn & Sensing Technol, Beijing 100083, Peoples R China 2.Chinese Acad Sci, Inst Proc Engn, Key Lab Green Proc & Engn, Beijing 100190, Peoples R China 3.Univ Laval, Dept Chem, Quebec City, PQ G1V 0A6, Canada 4.Univ Laval, Ctr Rech Mat Avances CERMA, Quebec City, PQ G1V 0A6, Canada 5.Univ Adelaide, Sch Chem Engn, Adelaide, SA 5005, Australia
推荐引用方式 GB/T 7714	Du, Xin,Li, Xiaoyu,Xiong, Lin,et al. Mesoporous silica nanoparticles with organo-bridged silsesquioxane framework as innovative platforms for bioimaging and therapeutic agent delivery[J]. BIOMATERIALS,2016,91(JUNE):90-127.
APA	Du, Xin,Li, Xiaoyu,Xiong, Lin,Zhang, Xueji,Kleitz, Freddy,&Qiao, Shi Zhang.(2016).Mesoporous silica nanoparticles with organo-bridged silsesquioxane framework as innovative platforms for bioimaging and therapeutic agent delivery.BIOMATERIALS,91(JUNE),90-127.
MLA	Du, Xin,et al."Mesoporous silica nanoparticles with organo-bridged silsesquioxane framework as innovative platforms for bioimaging and therapeutic agent delivery".BIOMATERIALS 91.JUNE(2016):90-127.