Engineering a natural Saccharomyces cerevisiae strain for ethanol production from inulin by consolidated bioprocessing

CORC > 青岛生物能源与过程研究所 > 中国科学院青岛生物能源与过程研究所 > 微生物资源团队

	Engineering a natural Saccharomyces cerevisiae strain for ethanol production from inulin by consolidated bioprocessing
	Wang, Da 1,2; Li, Fu-Li 1; Wang, Shi-An 1
刊名	BIOTECHNOLOGY FOR BIOFUELS
	2016-04-30
卷号	9
关键词	Yeast Inulin Ethanol Ploidy Consolidated bioprocessing Protein secretion
英文摘要	Background: The yeast Saccharomyces cerevisiae is an important eukaryotic workhorse in traditional and modern biotechnology. At present, only a few S. cerevisiae strains have been extensively used as engineering hosts. Recently, an astonishing genotypic and phenotypic diversity of S. cerevisiae was disclosed in natural populations. We suppose that some natural strains can be recruited as superior host candidates in bioengineering. This study engineered a natural S. cerevisiae strain with advantages in inulin utilization to produce ethanol from inulin resources by consolidated bioprocess. Rational engineering strategies were employed, including secretive co-expression of heterologous exo-and endo-inulinases, repression of a protease, and switch between haploid and diploid strains.
WOS标题词	Science & Technology ; Life Sciences & Biomedicine ; Technology
类目[WOS]	Biotechnology & Applied Microbiology ; Energy & Fuels
研究领域[WOS]	Biotechnology & Applied Microbiology ; Energy & Fuels
关键词[WOS]	JERUSALEM-ARTICHOKE TUBERS ; KLUYVEROMYCES-MARXIANUS ; BIOETHANOL PRODUCTION ; TRANSCRIPTIONAL ANALYSIS ; CELLULOSIC ETHANOL ; YEAST ; FERMENTATION ; POPULATION ; GENE ; EXPRESSION
收录类别	SCI
语种	英语
WOS记录号	WOS:000375096000001
内容类型	期刊论文
源URL	[http://ir.qibebt.ac.cn/handle/337004/8309]
专题	青岛生物能源与过程研究所_微生物资源团队
作者单位	1.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Shandong Prov Key Lab Synthet Biol, Qingdao 266101, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100039, Peoples R China
推荐引用方式 GB/T 7714	Wang, Da,Li, Fu-Li,Wang, Shi-An. Engineering a natural Saccharomyces cerevisiae strain for ethanol production from inulin by consolidated bioprocessing[J]. BIOTECHNOLOGY FOR BIOFUELS,2016,9.
APA	Wang, Da,Li, Fu-Li,&Wang, Shi-An.(2016).Engineering a natural Saccharomyces cerevisiae strain for ethanol production from inulin by consolidated bioprocessing.BIOTECHNOLOGY FOR BIOFUELS,9.
MLA	Wang, Da,et al."Engineering a natural Saccharomyces cerevisiae strain for ethanol production from inulin by consolidated bioprocessing".BIOTECHNOLOGY FOR BIOFUELS 9(2016).