Structure-oriented substrate specificity engineering of aldehyde-deformylating oxygenase towards aldehydes carbon chain length

CORC > 青岛生物能源与过程研究所 > 中国科学院青岛生物能源与过程研究所 > 微生物代谢工程团队

	Structure-oriented substrate specificity engineering of aldehyde-deformylating oxygenase towards aldehydes carbon chain length
	Bao, Luyao 1,3; Li, Jian-Jun 1,5; Jia, Chenjun 3,4; Li, Mei 4; Lu, Xuefeng 2
刊名	BIOTECHNOLOGY FOR BIOFUELS
	2016-08-31
卷号	9
关键词	Aldehyde-deformylating oxygenase Site-directed mutagenesis Structure-guided protein engineering Chain-length selectivity Synechococcus elongatus PCC7942
英文摘要	Background: Aldehyde-deformylating oxygenase (ADO) is an important enzyme involved in the biosynthetic pathway of fatty alk(a/e)nes in cyanobacteria. However, ADO exhibits quite low chain-length specificity with respect to the substrates ranging from C-4 to C-18 aldehydes, which is not suitable for producing fuels with different properties or different chain lengths.
WOS标题词	Science & Technology ; Life Sciences & Biomedicine ; Technology
类目[WOS]	Biotechnology & Applied Microbiology ; Energy & Fuels
研究领域[WOS]	Biotechnology & Applied Microbiology ; Energy & Fuels
关键词[WOS]	CYANOBACTERIAL ALDEHYDE ; FATTY-ACIDS ; ESCHERICHIA-COLI ; CARRIER PROTEIN ; E. COLI ; CONVERSION ; ALKANES ; DECARBONYLASE ; OVERPRODUCTION ; BIOSYNTHESIS
收录类别	SCI
语种	英语
WOS记录号	WOS:000383016100003
内容类型	期刊论文
源URL	[http://ir.qibebt.ac.cn/handle/337004/8419]
专题	青岛生物能源与过程研究所_微生物代谢工程团队
作者单位	1.Chinese Acad Sci, Key Lab Biofuels, Qingdao, Peoples R China 2.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Shandong Prov Key Lab Synthet Biol, 189 Songling Rd, Qingdao 266101, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 4.Chinese Acad Sci, Inst Biophys, Natl Lab Biomacromol, 15 Datun Rd, Beijing 100101, Peoples R China 5.Chinese Acad Sci, Inst Proc Engn, Natl Key Lab Biochem Engn, 1 North 2nd St, Beijing 100190, Peoples R China
推荐引用方式 GB/T 7714	Bao, Luyao,Li, Jian-Jun,Jia, Chenjun,et al. Structure-oriented substrate specificity engineering of aldehyde-deformylating oxygenase towards aldehydes carbon chain length[J]. BIOTECHNOLOGY FOR BIOFUELS,2016,9.
APA	Bao, Luyao,Li, Jian-Jun,Jia, Chenjun,Li, Mei,&Lu, Xuefeng.(2016).Structure-oriented substrate specificity engineering of aldehyde-deformylating oxygenase towards aldehydes carbon chain length.BIOTECHNOLOGY FOR BIOFUELS,9.
MLA	Bao, Luyao,et al."Structure-oriented substrate specificity engineering of aldehyde-deformylating oxygenase towards aldehydes carbon chain length".BIOTECHNOLOGY FOR BIOFUELS 9(2016).