Acylated neo-clerodane type diterpenoids from the aerial parts of Scutellaria coleifolia Levl. (Lamiaceae)
Kurimoto, Shin-ichiro1,3; Pu, Jian-Xin2; Sun, Han-Dong2; Shibata, Hirofumi1; Takaishi, Yoshihisa1; Kashiwada, Yoshiki1
刊名JOURNAL OF NATURAL MEDICINES
2016-04-01
卷号70期号:2页码:241-252
关键词Scutellaria coleifolia Lamiaceae Diterpenoid neo-Clerodane
英文摘要Twenty new neo-clerodane type diterpenoids, scutefolides G(1)-S (1-20), were isolated from the 70 % aqueous acetone extract of the aerial parts of Scutellaria coleifolia. Their structures were elucidated by extensive spectroscopic analyses. The absolute configurations of 1, 2, 7, 8, 14 and 15 were determined by means of the CD exciton chirality method. Compounds 1, 2, 5, 7, 8, 12, 14, 15, 18 and 19 were evaluated for their cytotoxic activities against four human cancer cell lines, and anti-bacterial activities against methicillin-resistant Staphylococcus aureus.
类目[WOS]Chemistry, Medicinal ; Pharmacology & Pharmacy
研究领域[WOS]Pharmacology & Pharmacy
关键词[WOS]NEO-CLERODANES ; BARBATA ; ALPINA ; CONSTITUENTS ; RIVULARIS
收录类别SCI
语种英语
WOS记录号WOS:000370365700013
内容类型期刊论文
源URL[http://ir.kib.ac.cn/handle/151853/25975]  
专题昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Univ Tokushima, Grad Sch Pharmaceut Sci, 1-78 Shomachi, Tokushima 7708505, Japan
2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China
3.Himeji Dokkyo Univ, Fac Pharmaceut Sci, 7-2-1 Kamiohno, Himeji, Hyogo 6708524, Japan
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Kurimoto, Shin-ichiro,Pu, Jian-Xin,Sun, Han-Dong,et al. Acylated neo-clerodane type diterpenoids from the aerial parts of Scutellaria coleifolia Levl. (Lamiaceae)[J]. JOURNAL OF NATURAL MEDICINES,2016,70(2):241-252.
APA Kurimoto, Shin-ichiro,Pu, Jian-Xin,Sun, Han-Dong,Shibata, Hirofumi,Takaishi, Yoshihisa,&Kashiwada, Yoshiki.(2016).Acylated neo-clerodane type diterpenoids from the aerial parts of Scutellaria coleifolia Levl. (Lamiaceae).JOURNAL OF NATURAL MEDICINES,70(2),241-252.
MLA Kurimoto, Shin-ichiro,et al."Acylated neo-clerodane type diterpenoids from the aerial parts of Scutellaria coleifolia Levl. (Lamiaceae)".JOURNAL OF NATURAL MEDICINES 70.2(2016):241-252.
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