Macroscopic and Fluorescent Discrimination of Adenosine Triphosphate via Selective Metallo-hydrogel Formation: A Visual, Practical, and Reliable Rehearsal toward Cellular Imaging

CORC > 烟台海岸带研究所 > 中国科学院烟台海岸带研究所 > 中科院海岸带环境过程与生态修复重点实验室

	Macroscopic and Fluorescent Discrimination of Adenosine Triphosphate via Selective Metallo-hydrogel Formation: A Visual, Practical, and Reliable Rehearsal toward Cellular Imaging
	Fang, WW; Liu, C; Yu, FB; Liu, YQ; Li, ZH; Chen, LX; Bao, XL; Tu, T
刊名	ACS APPLIED MATERIALS & INTERFACES
	2016-08-17
卷号	8 期号:32 页码:20583-20590
关键词	adenosine triphosphate celluar imaging fluorescence enhancement metallo-hydrogel visual recognition
ISSN号	1944-8244
通讯作者	Tu, T (reprint author), Fudan Univ, Dept Chem, 220 Handan Rd, Shanghai 200433, Peoples R China. ; Tu, T (reprint author), Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China. ; Chen, LX (reprint author), Chinese Acad Sci, Key Lab Coastal Environm Proc & Ecol Remediat, Res Ctr Coastal Environm Engn & Technol, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China. ; Bao, XL (reprint author), Shanghai Inst Qual Inspect & Tech Res, Inst Qual Inspect Food & Cosmet, 381 Cangwu Rd, Shanghai, Peoples R China. Email:lxchen@yic.ac.cn ; baoxl@sqi.org.cn ; taotu@fudan.edu.cn
产权排序	[Fang, Weiwei; Liu, Cong; Liu, Yaoqi; Li, Zhenhua; Tu, Tao] Fudan Univ, Dept Chem, 220 Handan Rd, Shanghai 200433, Peoples R China; [Tu, Tao] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China; [Yu, Fabiao; Chen, Lingxin] Chinese Acad Sci, Key Lab Coastal Environm Proc & Ecol Remediat, Res Ctr Coastal Environm Engn & Technol, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China; [Bao, Xiaoling] Shanghai Inst Qual Inspect & Tech Res, Inst Qual Inspect Food & Cosmet, 381 Cangwu Rd, Shanghai, Peoples R China
英文摘要	With use of simple terpyridine zinc nitrate complexes, intriguing visual recognition of adenosine triphosphate (ATP) via selective coordination assembly leading to two-component metallo-hydrogel formation has been realized. With intensive fluorescent study and density functional theory calculations, it may be inferred, besides the selective metal-ligand interaction between Zn center and phosphate groups, the intramolecular pi-stacking between the planar nucleobases of ATP and the metal-hybrid aromatic ring of pincer complex strongly affected the geometry of the coordinated adducts and possible molecular self-assembly process, which constitute a completely new sensing strategy in comparison with the conventional approaches. Furthermore, in light of extreme sensitivity of pincer zinc complexes toward ATP at micromolar scale (1.85 mu M) and remarkable fluorescent enhancement (ca. 44-fold) upon ATP addition, the feasibility of the low cytotoxicity pincer zinc complexes in monitoring ATP in HeLa Cells has been fulfilled with confocal fluorescence microscopy.
研究领域[WOS]	Science & Technology - Other Topics ; Materials Science
关键词[WOS]	MOLECULAR-MASS GELATORS ; SUPRAMOLECULAR GELS ; AQUEOUS-SOLUTION ; ARTIFICIAL RECEPTORS ; COLORIMETRIC SENSOR ; PHYSIOLOGICAL PH ; ORGANIC GELS ; ATP SENSOR ; RECOGNITION ; COORDINATION
收录类别	SCI
语种	英语
WOS记录号	WOS:000381715900010
内容类型	期刊论文
源URL	[http://ir.yic.ac.cn/handle/133337/17129]
专题	烟台海岸带研究所_中科院海岸带环境过程与生态修复重点实验室
推荐引用方式 GB/T 7714	Fang, WW,Liu, C,Yu, FB,et al. Macroscopic and Fluorescent Discrimination of Adenosine Triphosphate via Selective Metallo-hydrogel Formation: A Visual, Practical, and Reliable Rehearsal toward Cellular Imaging[J]. ACS APPLIED MATERIALS & INTERFACES,2016,8(32):20583-20590.
APA	Fang, WW.,Liu, C.,Yu, FB.,Liu, YQ.,Li, ZH.,...&Tu, T.(2016).Macroscopic and Fluorescent Discrimination of Adenosine Triphosphate via Selective Metallo-hydrogel Formation: A Visual, Practical, and Reliable Rehearsal toward Cellular Imaging.ACS APPLIED MATERIALS & INTERFACES,8(32),20583-20590.
MLA	Fang, WW,et al."Macroscopic and Fluorescent Discrimination of Adenosine Triphosphate via Selective Metallo-hydrogel Formation: A Visual, Practical, and Reliable Rehearsal toward Cellular Imaging".ACS APPLIED MATERIALS & INTERFACES 8.32(2016):20583-20590.