Three-dimensional periodic and fractal precipitation in metal ion-deoxycholate system: A model for gallstone formation

	Three-dimensional periodic and fractal precipitation in metal ion-deoxycholate system: A model for gallstone formation
	Xie, DT; Wu, JG; Xu, GX; Qi, OY; Soloway, RD; Hu, TD; Hu TD(胡天斗)
刊名	JOURNAL OF PHYSICAL CHEMISTRY B
	1999
卷号	103 期号:40 页码:8602-8605
通讯作者	Peking Univ, Dept Chem, Univ Hong Kong, Joint Lab Rare Earth Mat & Bioinorgan Chem, Beijing 100871, Peoples R China ; Peking Univ, Dept Phys, Beijing 100871, Peoples R China ; Univ Texas, Med Branch, Div Gastroenterol, Galveston, TX 77555 USA ; Inst High Energy Phys, Synchorotron Radiat Lab, Beijing 100039, Peoples R China
英文摘要	It was recently suggested that the periodic and fractal precipitation of calcium salts and proteins in cholesterol gallstonesis closely related to the process of stone formation. The present study is to mimic the process of gallstone growth in vitro. We demonstrate for the first time that a three-dimensional structure of periodic rings (Liesegang ring) and/or fractal patterns can be produced by metal ion and deoxycholate precipitation, which are similar to gallstones. Precipitation in a periodic pattern occurs more often than in a fractal structure. Using X-ray diffraction, polarized light microscope, Fourier transform-infrared (FT-IR), and extended X-ray absorption fine structure (EXAFS), we studied the pattern formation mechanisms of both types of structures. The results indicate that the rate of nucleation in the crystal growth is a crucial element to affect the pattern formation. The pattern selection between periodic and fractal type depends on the crystal growth speed and the rate of nucleation.
学科主题	Chemistry
类目[WOS]	Chemistry, Physical
研究领域[WOS]	Chemistry
原文出处	SCI
语种	英语
WOS记录号	WOS:000083151400026
内容类型	期刊论文
源URL	[http://ir.ihep.ac.cn/handle/311005/240145]
专题	高能物理研究所_多学科研究中心
作者单位	中国科学院高能物理研究所
推荐引用方式 GB/T 7714	Xie, DT,Wu, JG,Xu, GX,et al. Three-dimensional periodic and fractal precipitation in metal ion-deoxycholate system: A model for gallstone formation[J]. JOURNAL OF PHYSICAL CHEMISTRY B,1999,103(40):8602-8605.
APA	Xie, DT.,Wu, JG.,Xu, GX.,Qi, OY.,Soloway, RD.,...&胡天斗.(1999).Three-dimensional periodic and fractal precipitation in metal ion-deoxycholate system: A model for gallstone formation.JOURNAL OF PHYSICAL CHEMISTRY B,103(40),8602-8605.
MLA	Xie, DT,et al."Three-dimensional periodic and fractal precipitation in metal ion-deoxycholate system: A model for gallstone formation".JOURNAL OF PHYSICAL CHEMISTRY B 103.40(1999):8602-8605.