A PRELIMINARY-STUDY ON THE POSITIONAL DISTRIBUTION OF CISPLATIN AND OTHER ELEMENTS IN THE LIVER OF NORMAL MICE

	A PRELIMINARY-STUDY ON THE POSITIONAL DISTRIBUTION OF CISPLATIN AND OTHER ELEMENTS IN THE LIVER OF NORMAL MICE
	Liu NQ(刘年庆); YAN, LN; Li XJ(李学军); Chao ZY(巢志瑜); LIU, NQ; ZHOU, CN; YAN, LN; LI, XJ; CHAO, ZY; REN, ZG
刊名	NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS
	1993
卷号	75 期号:1-4 页码:571-575
通讯作者	CHINESE ACAD MED SCI,INST CANC,ELECTRON MICROSCOPE LAB,BEIJING 100021,PEOPLES R CHINA ; FUDAN UNIV,DEPT PHYS 2,SHANGHAI 200433,PEOPLES R CHINA
英文摘要	In the BEPC 4W1A station, synchrotron radiation has been used to induce X-ray fluorescence for measuring the concentration of elements in various materials, including biomedical samples. In this paper we present the 2D distribution map of platinum in liver slices of normal mice after Cisplatin treatment, and the correlation of the concentrations of the measured elements by mini-SXRF. The results show a positive correlation of the Fe concentration to those of Zn and Cu, and a positive relation of P to S in different points (150 x 150 mum2) of the liver slice. In order to obtain more information, the same sample has also been measured by micro-PIXE at Fudan University. The possibilities and limitations of the two probes for analyzing biomedical samples are discussed.
学科主题	Instruments & Instrumentation; Nuclear Science & Technology; Physics
类目[WOS]	Instruments & Instrumentation ; Nuclear Science & Technology ; Physics, Atomic, Molecular & Chemical ; Physics, Nuclear
研究领域[WOS]	Instruments & Instrumentation ; Nuclear Science & Technology ; Physics
原文出处	SCI
语种	英语
WOS记录号	WOS:A1993KY49800120
内容类型	期刊论文
源URL	[http://ir.ihep.ac.cn/handle/311005/237997]
专题	高能物理研究所_多学科研究中心
作者单位	中国科学院高能物理研究所
推荐引用方式 GB/T 7714	Liu NQ,YAN, LN,Li XJ,et al. A PRELIMINARY-STUDY ON THE POSITIONAL DISTRIBUTION OF CISPLATIN AND OTHER ELEMENTS IN THE LIVER OF NORMAL MICE[J]. NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS,1993,75(1-4):571-575.
APA	刘年庆.,YAN, LN.,李学军.,巢志瑜.,LIU, NQ.,...&ZHOU, SJ.(1993).A PRELIMINARY-STUDY ON THE POSITIONAL DISTRIBUTION OF CISPLATIN AND OTHER ELEMENTS IN THE LIVER OF NORMAL MICE.NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS,75(1-4),571-575.
MLA	刘年庆,et al."A PRELIMINARY-STUDY ON THE POSITIONAL DISTRIBUTION OF CISPLATIN AND OTHER ELEMENTS IN THE LIVER OF NORMAL MICE".NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS 75.1-4(1993):571-575.