EGFP-Based Protein Nanoparticles with Cell-Penetrating Peptide for Efficient siRNA Delivery

	EGFP-Based Protein Nanoparticles with Cell-Penetrating Peptide for Efficient siRNA Delivery
	Guan,Xingang; Hu,Xiuli; Cui,Fengchao; Li,Yunqi; Jing,Xiabing; Xie,Zhigang
刊名	macromolecular bioscience
	2015
卷号	15 期号:11 页码:1484-1489
关键词	MESOPOROUS SILICA NANOPARTICLES DRUG-DELIVERY IN-VIVO CANCER-THERAPY INTRACELLULAR TRAFFICKING GOLD NANOPARTICLES SYSTEM NANOCARRIERS TUMORS VITRO
通讯作者	li,yq
英文摘要	development of an innovative nucleic acid nanocarriers still represents a challenge. in this study, we develop a protein nanoparticle (h6-tategfp) and examine its sirna condensing activity. gel retardation assay show that protein nanoparticle can condense sirna into stable nanoparticle/sirna complexes. usingcy3-labelled sirna, we also evaluate sirna transport characteristic of protein nanoparticles in tumor cells, the results indicate that h6-tategfp nanoparticle may be a potential nanocarrier for sirna in tumor cells.
收录类别	SCI
语种	英语
公开日期	2016-05-31
内容类型	期刊论文
源URL	[http://ir.ciac.jl.cn/handle/322003/67807]
专题	长春应用化学研究所_长春应用化学研究所知识产出_期刊论文
推荐引用方式 GB/T 7714	Guan,Xingang,Hu,Xiuli,Cui,Fengchao,et al. EGFP-Based Protein Nanoparticles with Cell-Penetrating Peptide for Efficient siRNA Delivery[J]. macromolecular bioscience,2015,15(11):1484-1489.
APA	Guan,Xingang,Hu,Xiuli,Cui,Fengchao,Li,Yunqi,Jing,Xiabing,&Xie,Zhigang.(2015).EGFP-Based Protein Nanoparticles with Cell-Penetrating Peptide for Efficient siRNA Delivery.macromolecular bioscience,15(11),1484-1489.
MLA	Guan,Xingang,et al."EGFP-Based Protein Nanoparticles with Cell-Penetrating Peptide for Efficient siRNA Delivery".macromolecular bioscience 15.11(2015):1484-1489.