Fluorescence imaging of metal ions implicated in diseases

	Fluorescence imaging of metal ions implicated in diseases
	Qian, Xuhong 1; Xu, Zhaochao 2
刊名	chemical society reviews
	2015
卷号	44 期号:14 页码:4487-4493
英文摘要	metal ions play an important role in various biological processes, their abnormal homeostasis in cells is related to many diseases, such as neurodegenerative disease, cancer and diabetes. fluorescent imaging offers a unique route to detect metal ions in cells via a contactless and damage-free way with high spatial and temporal fidelity. consequently, it represents a promising method to advance the understanding of physiological and pathological functions of metal ions in cell biology. in this highlight article, we will discuss recent advances in fluorescent imaging of metal ions by small-molecule sensors for understanding the role of metals in related diseases. we will also discuss challenges and opportunities for the design of small-molecule sensors for fluorescent detection of cellular metal ions as a potential method for disease diagnosis.
WOS标题词	science & technology ; physical sciences
类目[WOS]	chemistry, multidisciplinary
研究领域[WOS]	chemistry
关键词[WOS]	living cells ; oxidative stress ; aqueous-solution ; zinc ion ; hippocampal slices ; live cells ; sensor ; zn2+ ; probe ; indicator
收录类别	SCI
语种	英语
WOS记录号	WOS:000357691200002
公开日期	2016-05-09
内容类型	期刊论文
源URL	[http://cas-ir.dicp.ac.cn/handle/321008/146381]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
作者单位	1.E China Univ Sci & Technol, State Key Lab Bioreactor Engn, Shanghai Key Lab Chem Biol, Sch Pharm, Shanghai 200237, Peoples R China 2.Chinese Acad Sci, Dalian Inst Chem Phys, Key Lab Separat Sci Analyt Chem CAS, Dalian 116023, Peoples R China
推荐引用方式 GB/T 7714	Qian, Xuhong,Xu, Zhaochao. Fluorescence imaging of metal ions implicated in diseases[J]. chemical society reviews,2015,44(14):4487-4493.
APA	Qian, Xuhong,&Xu, Zhaochao.(2015).Fluorescence imaging of metal ions implicated in diseases.chemical society reviews,44(14),4487-4493.
MLA	Qian, Xuhong,et al."Fluorescence imaging of metal ions implicated in diseases".chemical society reviews 44.14(2015):4487-4493.