Aligned Electroactive TMV Nanofibers as Enabling Scaffold for Neural Tissue Engineering

	Aligned Electroactive TMV Nanofibers as Enabling Scaffold for Neural Tissue Engineering
	Wu,Yehong; Feng,Sheng; Zan,Xingjie; Lin,Yuan; Wang,Qian
刊名	biomacromolecules
	2015
卷号	16 期号:11 页码:3466-3472
关键词	TOBACCO-MOSAIC-VIRUS PC12 DIFFERENTIATION NERVE REGENERATION CELL ALIGNMENT POLYANILINE GROWTH STIMULATION ORIENTATION TEMPLATE ADHESION
通讯作者	lin,y
英文摘要	electroactive nanofibers were fabricated by in situ polymerization of aniline on the surface of tobacco mosaic virus (tmv) using sodium poly(styrenesulfonate) (pss) as dopant. these electroactive tmv/pani/pss nanofibers were employed to support growth of neuronal cells, resulting in augmentation of the length of neurites. in addition, the percentage of cells with neurites was increased in comparison to cells cultured on tmv-derived nonconductive nanofibers. the tmv-based electroactive nanofibers could be aligned in capillaries that could guide the outgrowth direction of neurites, increase the percentage of cells with neurites, and lead to a bipolar cellular morphology. our results demonstrate that the electroactivity and topographical cues provided by tmv/pani/pss nanofibers can synergistically stimulate neural cells differentiation and neurites outgrowth, which make it a promising scaffolding material for neural tissue engineering.
收录类别	SCI
语种	英语
WOS记录号	WOS:000364614300006
内容类型	期刊论文
源URL	[http://ir.ciac.jl.cn/handle/322003/64820]
专题	长春应用化学研究所_长春应用化学研究所知识产出_期刊论文
推荐引用方式 GB/T 7714	Wu,Yehong,Feng,Sheng,Zan,Xingjie,et al. Aligned Electroactive TMV Nanofibers as Enabling Scaffold for Neural Tissue Engineering[J]. biomacromolecules,2015,16(11):3466-3472.
APA	Wu,Yehong,Feng,Sheng,Zan,Xingjie,Lin,Yuan,&Wang,Qian.(2015).Aligned Electroactive TMV Nanofibers as Enabling Scaffold for Neural Tissue Engineering.biomacromolecules,16(11),3466-3472.
MLA	Wu,Yehong,et al."Aligned Electroactive TMV Nanofibers as Enabling Scaffold for Neural Tissue Engineering".biomacromolecules 16.11(2015):3466-3472.