Near-infrared absorbing mesoporous carbon nanoparticle as an intelligent drug carrier for dual-triggered synergistic cancer therapy

	Near-infrared absorbing mesoporous carbon nanoparticle as an intelligent drug carrier for dual-triggered synergistic cancer therapy
	Zhou,Li; Dong,Kai; Chen,Zhaowei; Ren,Jinsong; Qu,Xiaogang
刊名	carbon
	2015
卷号	82 页码:479-488
关键词	GUIDED PHOTOTHERMAL THERAPY GRAPHENE OXIDE HYALURONIC-ACID MAGNETIC NANOPARTICLES SILICA NANOPARTICLES THERMO-CHEMOTHERAPY GOLD NANOPARTICLES DELIVERY VEHICLE IRON-OXIDE CELLS
通讯作者	ren,js
英文摘要	herein a novel multifunctional nanoplatform based on surface engineered mesoporous carbon nanoparticle (mcn) is developed for effective dual-triggered synergistic cancer therapy. mcns employed in the study not only function as near-infrared absorbing agents but also as nanocarriers with a high drug loading efficiency. the surface modification of mcn with biomacromolecules (hyaluronic acid) through disulfide unit makes the system be sensitive to both intracellular hyaluronidase-1 and gsh to release the carried drug. the hyaluronic acid on mcn simultaneously confers the system biocompatibility and a cancer cell targeting ability. by combining these capabilities, the multifunctional nanoplatform shows an effective therapeutic efficiency toward the target cells. (c) 2014 elsevier ltd. all rights reserved.
收录类别	SCI
语种	英语
公开日期	2016-05-09
内容类型	期刊论文
源URL	[http://ir.ciac.jl.cn/handle/322003/64796]
专题	长春应用化学研究所_长春应用化学研究所知识产出_期刊论文
推荐引用方式 GB/T 7714	Zhou,Li,Dong,Kai,Chen,Zhaowei,et al. Near-infrared absorbing mesoporous carbon nanoparticle as an intelligent drug carrier for dual-triggered synergistic cancer therapy[J]. carbon,2015,82:479-488.
APA	Zhou,Li,Dong,Kai,Chen,Zhaowei,Ren,Jinsong,&Qu,Xiaogang.(2015).Near-infrared absorbing mesoporous carbon nanoparticle as an intelligent drug carrier for dual-triggered synergistic cancer therapy.carbon,82,479-488.
MLA	Zhou,Li,et al."Near-infrared absorbing mesoporous carbon nanoparticle as an intelligent drug carrier for dual-triggered synergistic cancer therapy".carbon 82(2015):479-488.