Synthesis of amphiphilic reduced graphene oxide with an enhanced charge injection capacity for electrical stimulation of neural cells

CORC > 苏州纳米技术与纳米仿生研究所 > 中国科学院苏州纳米技术与纳米仿生研究所 > 纳米器件及相关材料研究部 > 刘立伟团队

	Synthesis of amphiphilic reduced graphene oxide with an enhanced charge injection capacity for electrical stimulation of neural cells
	Song, Q (宋琴); Cheng, GS (程国胜); Liu, LW (刘立伟)
刊名	JOURNAL OF MATERIALS CHEMISTRY B
	2014
卷号	2 期号:27 页码:4331-4337
关键词	NANOSHEETS REDUCTION NEURONS
通讯作者	Liu, J (Liu, Jian)
英文摘要	Advanced neural research demands new electrode materials with high performance. Herein, we have developed a facile approach to synthesize amphiphilic reduced graphene oxide (rGO) and demonstrated its performance in electrically stimulating neural cells with high charge injection capacity. Synthesis of the amphiphilic rGO features covalent functionalization and simultaneous thermal reduction in a one-step manner. The covalent functionalization of methoxy poly(ethylene glycol) (mPEG) chains on the rGO surface not only provides a high dispersibility in various solvents, enabling convenient post-treatment processes, but also allows for an enhancement in double-layer charging capacitance. Calcium imaging of PC12 neural cells on the amphiphilic mPEG-rGO films has revealed a predominant increase in the percentage of cells with higher action potentials, derived from double-layer capacitance enhancement in charge injection. These results suggest that the new amphiphilic mPEG-rGO material is capable of providing a much safer and efficacious solution for neural prostheses applications.
收录类别	SCI
语种	英语
WOS记录号	WOS:000338124900014
公开日期	2015-02-03
内容类型	期刊论文
源URL	[http://ir.sinano.ac.cn/handle/332007/1735]
专题	苏州纳米技术与纳米仿生研究所_纳米器件及相关材料研究部_刘立伟团队苏州纳米技术与纳米仿生研究所_纳米生物医学与安全研究部_程国胜团队
推荐引用方式 GB/T 7714	Song, Q ,Cheng, GS ,Liu, LW . Synthesis of amphiphilic reduced graphene oxide with an enhanced charge injection capacity for electrical stimulation of neural cells[J]. JOURNAL OF MATERIALS CHEMISTRY B,2014,2(27):4331-4337.
APA	Song, Q ,Cheng, GS ,&Liu, LW .(2014).Synthesis of amphiphilic reduced graphene oxide with an enhanced charge injection capacity for electrical stimulation of neural cells.JOURNAL OF MATERIALS CHEMISTRY B,2(27),4331-4337.
MLA	Song, Q ,et al."Synthesis of amphiphilic reduced graphene oxide with an enhanced charge injection capacity for electrical stimulation of neural cells".JOURNAL OF MATERIALS CHEMISTRY B 2.27(2014):4331-4337.