Monitoring of Tumor Response to Au Nanorod-Indocyanine Green Conjugates Mediated Therapy With Fluorescence Imaging and Positron Emission Tomography

	Monitoring of Tumor Response to Au Nanorod-Indocyanine Green Conjugates Mediated Therapy With Fluorescence Imaging and Positron Emission Tomography
	Liu, F; Zhang,刘双全; 单保慈; Y; Liu, SQ; Zhang, B; Liu, Q; Yang, Y; Zhang, B; Luo, JW; Shan, BC
刊名	IEEE TRANSACTIONS ON MULTIMEDIA
	2013
卷号	15 期号:5 页码:1025-1030
关键词	Dual-modality imaging fluorescence photodynamic therapy photothermal therapy [F-18]FDG-PET
英文摘要	Fluorescence imaging can track the expression of fluorescent protein and F-18-fluorodeoxyglucose based positron emission tomography ([F-18]FDG-PET) can evaluate the changes of [F-18]FDG uptake in tumor cells during the antitumor treatment. In this work, fluorescence imaging and [F-18]FDG-PET were both employed to monitor tumor response to Au nanorod-indocyanine green (AuNR-ICG) conjugates mediated therapy in a subcutaneous MDA-MB-231 mouse xenograft model. Serial fluorescence and [F-18]FDG-PET images following the antitumor treatment were obtained and quantitative analysis revealed significant decreases in fluorescence intensity and metabolic activity in tumors treated with AuNR-ICG conjugates under near infrared laser irradiation. The results suggest that the combination of fluorescence and [F-18]FDG-PET imaging can provide a noninvasive tool to assess the tumor response to antitumor therapy on a molecular scale.
学科主题	Computer Science; Telecommunications
收录类别	SCI
WOS记录号	WOS:000324763600006
公开日期	2016-05-03
内容类型	期刊论文
源URL	[http://ir.ihep.ac.cn/handle/311005/224097]
专题	中国科学院高能物理研究所
推荐引用方式 GB/T 7714	Liu, F,Zhang,刘双全,单保慈； Y,et al. Monitoring of Tumor Response to Au Nanorod-Indocyanine Green Conjugates Mediated Therapy With Fluorescence Imaging and Positron Emission Tomography[J]. IEEE TRANSACTIONS ON MULTIMEDIA,2013,15(5):1025-1030.
APA	Liu, F.,Zhang,刘双全.,单保慈； Y.,Liu, SQ.,Zhang, B.,...&Bai, J.(2013).Monitoring of Tumor Response to Au Nanorod-Indocyanine Green Conjugates Mediated Therapy With Fluorescence Imaging and Positron Emission Tomography.IEEE TRANSACTIONS ON MULTIMEDIA,15(5),1025-1030.
MLA	Liu, F,et al."Monitoring of Tumor Response to Au Nanorod-Indocyanine Green Conjugates Mediated Therapy With Fluorescence Imaging and Positron Emission Tomography".IEEE TRANSACTIONS ON MULTIMEDIA 15.5(2013):1025-1030.