Syntheses, Structures and Antioxidant Activities of Fullerenols: Knowledge Learned at the Atomistic Level

	Syntheses, Structures and Antioxidant Activities of Fullerenols: Knowledge Learned at the Atomistic Level
	Wang ZZ(王真真); Wang, ZZ; Wang, SK; Lu, ZH; Gao, XF; Gao XF(高兴发)
刊名	JOURNAL OF CLUSTER SCIENCE
	2015
卷号	26 期号:2 页码:375-388
关键词	Fullerenols Synthesis Structure Reaction mechanism Antioxidant activity
通讯作者	高兴发
英文摘要	Fullerenol nanoparticles have intriguing potentials in biomedical applications. However, the structures, mechanisms of syntheses and mechanisms of antioxidant activities of fullerenols at the atomistic level, which substantialize their properties and applications, remain opened questions. Here, we review the syntheses, structures and antioxidant activities of fullerenols. Especially, we focus on the knowledge at the atomistic level. Experimentally, fullerenols can be synthesized using oxidation reactions in either acidic conditions or alkaline conditions. The latter reactions yield fullerenols with high hydroxyl numbers and better water solubility. For fullerenol structures, a precision structural model has been recently proposed for C-60 fullerenols, which explain the experimentally-observed radical anion properties and pH-dependent infrared spectroscopic properties. Calculations have suggested that the most thermodynamically stable structures of many fullerenols have hydroxyls located aggregately in islands on the fullerene cages, although the most stable configuration of C-60(OH)(24) has hydroxyls distributed on C-60 equator. Two different center dot OH-scavenging mechanisms are possible for fullerenols. Fullerenols with low degrees of hydroxylation prefer the center dot OH addition mechanism, whereas those with high degrees of hydroxylation prefer the hydrogen abstraction mechanism. The O (2) (a (TM) a') -scavenging mechanism is related to redox potentials, charges and H-bond nets of the fullerenols.
学科主题	Chemistry
类目[WOS]	Chemistry, Inorganic & Nuclear
收录类别	SCI
WOS记录号	WOS:000351310300006
公开日期	2016-05-03
内容类型	期刊论文
源URL	[http://ir.ihep.ac.cn/handle/311005/228249]
专题	中国科学院高能物理研究所
推荐引用方式 GB/T 7714	Wang ZZ,Wang, ZZ,Wang, SK,et al. Syntheses, Structures and Antioxidant Activities of Fullerenols: Knowledge Learned at the Atomistic Level[J]. JOURNAL OF CLUSTER SCIENCE,2015,26(2):375-388.
APA	王真真,Wang, ZZ,Wang, SK,Lu, ZH,Gao, XF,&高兴发.(2015).Syntheses, Structures and Antioxidant Activities of Fullerenols: Knowledge Learned at the Atomistic Level.JOURNAL OF CLUSTER SCIENCE,26(2),375-388.
MLA	王真真,et al."Syntheses, Structures and Antioxidant Activities of Fullerenols: Knowledge Learned at the Atomistic Level".JOURNAL OF CLUSTER SCIENCE 26.2(2015):375-388.