Occurrences of pharmaceuticals in drinking water sources of major river watersheds, China

CORC > 生态环境研究中心 > 中国科学院生态环境研究中心 > 环境水质学国家重点实验室

	Occurrences of pharmaceuticals in drinking water sources of major river watersheds, China
	Sun, Jing; Luo, Qian; Wang, Donghong; Wang, Zijian
刊名	ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
	2015-07
卷号	117 页码:132-140
关键词	Pharmaceutical Drinking water Occurrence in China Causality analysis
英文摘要	Pharmaceuticals in drinking water sources (DWSs) have raised significant concerns for their persistent input and potential human health risks. Currently, little is known about the occurrence of pharmaceuticals in DWSs in China. In this study, a survey for multi-class pharmaceuticals in DWSs of five major river watersheds in China was conducted from 2012 to 2013. Samples were collected from 25 sampling sites in rivers and reservoirs. 135 pharmaceuticals were analyzed using solid-phase extraction and ultra-performance liquid chromatography tandem mass spectrometry. The results showed that a total of 70 pharmaceuticals were present in the samples, and the most frequently detected ones included sulfonamides, macrolides, antiepileptic drugs, anti-inflammatory drugs, and beta-blockers, etc. Amongst these, maximum concentrations of lincomycin, sulfamethoxazole, acetaminophen and paraxanthine were between 44 ng/L and 134 ng/L, and those of metoprolol, diphenhydramine, venlafaxine, nalidixic acid and androstenedione were less than 1 ng/L. Concentrations of the two that were most persistent, DEET and carbamazepine, were 0.8-10.2 ng/L and 0.01-3.5 ng/L, respectively. Higher concentrations of cotinine were observed in warm season than in cold season, while concentrations of lincomycin were the opposite. In a causality analysis, the occurrence of pharmaceuticals in DWSs depends mainly on the detection limits of the methods, their usage and the persistence in the aquatic environment. (C) 2015 Elsevier Inc. All rights reserved.
研究领域[WOS]	Environmental Sciences ; Toxicology
WOS记录号	WOS:000354501500015
公开日期	2016-03-15
内容类型	期刊论文
源URL	[http://ir.rcees.ac.cn/handle/311016/32812]
专题	生态环境研究中心_环境水质学国家重点实验室
推荐引用方式 GB/T 7714	Sun, Jing,Luo, Qian,Wang, Donghong,et al. Occurrences of pharmaceuticals in drinking water sources of major river watersheds, China[J]. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,2015,117:132-140.
APA	Sun, Jing,Luo, Qian,Wang, Donghong,&Wang, Zijian.(2015).Occurrences of pharmaceuticals in drinking water sources of major river watersheds, China.ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,117,132-140.
MLA	Sun, Jing,et al."Occurrences of pharmaceuticals in drinking water sources of major river watersheds, China".ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY 117(2015):132-140.