A reversible fluorescence probe for detection of ClO-/AA redox cycle in aqueous solution and in living cells
Wang JM(王佳敏)1,2,3; Ni Y(倪月)1,2,3; Shao SJ(邵士俊)1,2
刊名Talanta
2016
卷号147页码:468-472
关键词Fluorescent probe 7-Nitrobenzoxadiazole (NBD) Redox cycle ClO- Bioimaging
ISSN号0039-9140
通讯作者邵士俊
英文摘要

Based on the reversible redox reaction of 4-amino-2,2,6,6-tetramethyl-piperidin-1-ol with oxidative ClO and reductive ascorbic acid (AA), a reversible fluorescent probe, incorporating 4-amino-2,2,6,6-tetramethyl-piperidin-1-ol group into a 7-nitrobenzoxadiazole (NBD) fluorophore, was synthesized and studied for the cyclic detection of ClO/AA in aqueous solution. The NBD-based probe displayed sensitive and selective On–Off–On fluorescent responses to ClO/AA and was successfully applied to monitor the ClO/AA redox cycle in living HeLa cells under physiological conditions.

学科主题分析化学与药物化学
收录类别SCI
资助信息the National Natural Science Foundation of China (20972170;21275150);the Funds for Distinguished Young Scientists of Gansu (1210RJDA013)
语种英语
WOS记录号WOS:000366078200066
内容类型期刊论文
源URL[http://210.77.64.217/handle/362003/19142]  
专题兰州化学物理研究所_中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室
作者单位1.Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Chem Northwestern Plant Resources, Lanzhou 730000, Peoples R China
2.Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Nat Med Gansu Prov, Lanzhou 730000, Peoples R China
3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式
GB/T 7714
Wang JM,Ni Y,Shao SJ. A reversible fluorescence probe for detection of ClO-/AA redox cycle in aqueous solution and in living cells[J]. Talanta,2016,147:468-472.
APA Wang JM,Ni Y,&Shao SJ.(2016).A reversible fluorescence probe for detection of ClO-/AA redox cycle in aqueous solution and in living cells.Talanta,147,468-472.
MLA Wang JM,et al."A reversible fluorescence probe for detection of ClO-/AA redox cycle in aqueous solution and in living cells".Talanta 147(2016):468-472.
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