Further New Xenicanes from a Chinese Collection of the Brown Alga Dictyota plectens
Zhao, Min1; Cheng, Shimiao2; Yuan, Weiping1; Dong, Jianyong1; Huang, Kexin1; Sun, Zhongmin3; Yan, Pengcheng1
刊名CHEMICAL & PHARMACEUTICAL BULLETIN
2015-12-01
卷号63期号:12页码:1081-1086
关键词brown alga Dictyota plectens xenicane antiviral property nitric oxide (NO) inhibition
英文摘要Four new xenicanes, namely 4a-hydroxyisodictyohemiacetal (1), 4a-hydroxyisodictyoacetal (2), 13,18-diacetoxy-4-hydroxyisodictyo-19-al (3), and 4a-hydroxypachylactone (8), were isolated from a Chinese collection of the brown alga Dictyota plectens, along with four known analogues (4-7). The structures of the new diterpenes were determined by extensive spectroscopic data analysis. All compounds were evaluated for their antiviral activities against human immunodeficiency virus type 1 (HIV-1) and the highly pathogenic avian influenza A (H5N1) virus, and inhibitory effects on lipopolysaccharide (LPS)-induced nitric oxide (NO) production in mouse peritoneal macrophages (PEM Phi).
收录类别SCI
语种英语
WOS记录号WOS:000365694900014
内容类型期刊论文
源URL[http://ir.qdio.ac.cn/handle/337002/86537]  
专题海洋研究所_海洋生物分类与系统演化实验室
作者单位1.Wenzhou Med Univ, Sch Pharmaceut Sci, Wenzhou 325035, Zhejiang, Peoples R China
2.Wenzhou Med Univ, Affiliated Hosp 1, Lishui 323000, Zhejiang, Peoples R China
3.Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Shandong, Peoples R China
推荐引用方式
GB/T 7714
Zhao, Min,Cheng, Shimiao,Yuan, Weiping,et al. Further New Xenicanes from a Chinese Collection of the Brown Alga Dictyota plectens[J]. CHEMICAL & PHARMACEUTICAL BULLETIN,2015,63(12):1081-1086.
APA Zhao, Min.,Cheng, Shimiao.,Yuan, Weiping.,Dong, Jianyong.,Huang, Kexin.,...&Yan, Pengcheng.(2015).Further New Xenicanes from a Chinese Collection of the Brown Alga Dictyota plectens.CHEMICAL & PHARMACEUTICAL BULLETIN,63(12),1081-1086.
MLA Zhao, Min,et al."Further New Xenicanes from a Chinese Collection of the Brown Alga Dictyota plectens".CHEMICAL & PHARMACEUTICAL BULLETIN 63.12(2015):1081-1086.
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