Intramolecular Cooperative C-C Bond Cleavage Reaction of 1,3-Dicarbonyl Compounds with 2-Iodoanilines to Give o-(N-Acylamino)aryl Ketones and Multisubstituted Indoles | |
Xing Q(邢琦)1,2; Lv H(吕辉)1; Xia CG(夏春谷)1; Li FW(李福伟)1; Li FW(李福伟) | |
刊名 | Chemistry - A European Journal |
2015 | |
卷号 | 21期号:23页码:8591-8596 |
关键词 | C-C bond cleavage copper domino reactions ortho effect reaction mechanisms |
ISSN号 | 0947-6539 |
通讯作者 | 李福伟 |
英文摘要 | A copper-catalyzed CC bond cleavage reaction of 1,3-dicarbonyl compounds with 2-iodoanilines was developed. In this process, the ortho effect played an important role in the reactivity and a new reaction pathway that involved a (2-aminophenyl)-bis-(1,3-dicarbonyl) copper species was clearly observed by a time-course HRMS analysis of the reaction mixture. Unlike the previous reports, both the nucleophilic and electrophilic parts of the 1,3-dicarbonyl compound were coupled with 2-iodoaniline by CC bond cleavage to form o-(N-acylamino)aryl ketones, which could be efficiently converted into multisubstituted indoles. |
学科主题 | 物理化学与绿色催化 |
收录类别 | SCI |
资助信息 | the Chinese Academy of Sciences;the National Natural Science Foundation of China (21133011;21373246) |
语种 | 英语 |
WOS记录号 | WOS:000355260000038 |
内容类型 | 期刊论文 |
源URL | [http://210.77.64.217/handle/362003/18450] |
专题 | 兰州化学物理研究所_OSSO国家重点实验室 |
通讯作者 | Li FW(李福伟) |
作者单位 | 1.Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Oxo Synth Oxidat, Lanzhou 730000, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China |
推荐引用方式 GB/T 7714 | Xing Q,Lv H,Xia CG,et al. Intramolecular Cooperative C-C Bond Cleavage Reaction of 1,3-Dicarbonyl Compounds with 2-Iodoanilines to Give o-(N-Acylamino)aryl Ketones and Multisubstituted Indoles[J]. Chemistry - A European Journal,2015,21(23):8591-8596. |
APA | Xing Q,Lv H,Xia CG,Li FW,&李福伟.(2015).Intramolecular Cooperative C-C Bond Cleavage Reaction of 1,3-Dicarbonyl Compounds with 2-Iodoanilines to Give o-(N-Acylamino)aryl Ketones and Multisubstituted Indoles.Chemistry - A European Journal,21(23),8591-8596. |
MLA | Xing Q,et al."Intramolecular Cooperative C-C Bond Cleavage Reaction of 1,3-Dicarbonyl Compounds with 2-Iodoanilines to Give o-(N-Acylamino)aryl Ketones and Multisubstituted Indoles".Chemistry - A European Journal 21.23(2015):8591-8596. |
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