Biocompatibility of borosilicate glass-ceramics based LTCC materials for microfluidic biosensor application

doi:10.1111/ijac.13357

	Biocompatibility of borosilicate glass-ceramics based LTCC materials for microfluidic biosensor application
	Liang, Yongyuan; Ma, Mingsheng; Qian, Suxiang; Zhuang, Hui; Li, Kunqiang; Liu, Zhifu; Li, Yongxiang
刊名	INTERNATIONAL JOURNAL OF APPLIED CERAMIC TECHNOLOGY
	2019-12-31
关键词	borosilicate glass dielectric materials properties glass-ceramics
ISSN号	1546-542X
DOI	10.1111/ijac.13357
文献子类	Article; Early Access
英文摘要	Three kinds of borosilicate glass-ceramics Low temperature co-fired ceramics (LTCC) substrate materials, Ca-B-Si-O (CBS), Ca-Al-B-Si-O (CABS), and Ca-Mg-B-Si-O (CMBS), have been prepared, and the biocompatibility of these materials was evaluated. Compared with CBS and CMBS samples, the CABS sample presented the lowest crystallinity and dissolution in the bioleaching experiments. The direct and indirect cell culturing results showed that the CABS sample also possessed the best biocompatibility to the bone mesenchymal stem cells (BMSCs) due to its good bio-stability and surface micro-pore structure. The effects of surface topography and released ions on cytocompatibility were analyzed. These results were expected to offer some guideline information for developing LTCC substrate materials used in the microfluidic biosensors for the future biological and medical application.
WOS关键词	IN-VITRO BIOACTIVITY ; COMPOSITE ; SCAFFOLDS
WOS研究方向	Materials Science
语种	英语
出版者	WILEY
内容类型	期刊论文
源URL	[http://ir.sic.ac.cn/handle/331005/27545]
专题	中国科学院上海硅酸盐研究所
推荐引用方式 GB/T 7714	Liang, Yongyuan,Ma, Mingsheng,Qian, Suxiang,et al. Biocompatibility of borosilicate glass-ceramics based LTCC materials for microfluidic biosensor application[J]. INTERNATIONAL JOURNAL OF APPLIED CERAMIC TECHNOLOGY,2019.
APA	Liang, Yongyuan.,Ma, Mingsheng.,Qian, Suxiang.,Zhuang, Hui.,Li, Kunqiang.,...&Li, Yongxiang.(2019).Biocompatibility of borosilicate glass-ceramics based LTCC materials for microfluidic biosensor application.INTERNATIONAL JOURNAL OF APPLIED CERAMIC TECHNOLOGY.
MLA	Liang, Yongyuan,et al."Biocompatibility of borosilicate glass-ceramics based LTCC materials for microfluidic biosensor application".INTERNATIONAL JOURNAL OF APPLIED CERAMIC TECHNOLOGY (2019).